Frequently Asked Questions

What are the ASPIRE HEMOPHILIA research awards
ASPIRE stands for Advancing Science through Pfizer - Investigator Research Exchange and is a competitive grants program sponsored by Pfizer.
The ASPIRE HEMOPHILIA program utilizes an independent, external expert panel to review and select the successful grant applications. The ASPIRE HEMOPHILIA program is designed to support basic science and clinical research in Hemophilia pathogenesis, host response and clinical outcomes in Hemophilia A as well as translation of the resulting knowledge to bridge the gap between bench and bedside. (top)

Who is eligible to apply for ASPIRE HEMOPHILIA Research awards?
To be eligible, applicants must have a professional degree (e.g. MD, PhD, PharmD) and reside in the United States. Mid-career or Senior Investigators are encouraged to apply, however, in order to stimulate the careers of young investigators, preference will be given to those investigators who are currently conducting postdoctoral PhD research or within 5 years of fellowship completion. Applicants currently enrolled in a residency or fellowship program are not eligible. (top)

What is the role of Pfizer in the ASPIRE HEMOPHILIA Research awards?
While Pfizer will fully fund the ASPIRE HEMOPHILIA Research awards, applications will be reviewed and grant awardees will be selected by an independent, external expert panel. Pfizer will provide infrastructure and administrative support to facilitate the application and the review process as well as notify applicants and distribute awards. (top)

How many ASPIRE HEMOPHILIA Research awards are available?
Approximately 1-5 awards. The amount of each award will be approximately $125,000 per year, inclusive of institutional overhead. Yearly grant monies will be distributed at 50% at the beginning of the award year and 50% upon submission of the yearly grant progress / final report (top)

When will the ASPIRE HEMOPHILIA Research awards for 2014 be announced?
The successful awardees will be notified in the Summer. (top)

Is the funding a per-annum or per-study amount?
Yearly grant monies will be distributed on a per-annum basis. (top)

Does the funding include Institutional overhead costs and indirect costs?
Yes, the funding award includes indirect costs, and institutional overhead costs. Final budgets of those studies awarded a grant will be reviewed for fair market value before the contracting process begins. (top)

What are indirect costs?
Indirect costs are additional study expenses such as costs for publication, IRB/IEC review fees, supplies, software license fees, and travel. (top)

What are institutional overhead costs?
Institutional overhead costs, are costs to the institution for the support of your study. They are not easily identifiable in an economically feasible way as exclusively related to a particular project but are necessary to conduct the grant. Some examples of these costs are human resources department costs, payroll processing and accounting costs, janitorial services, utilities, property taxes, property and liability insurance, and building maintenance. (top)

How are the funds dispersed?
The awards will be paid in milestones and/or per-annum. (top)

How may the ASPIRE HEMOPHILIA Research funding be used?
Funds may be used to cover the awardees’ salary and fringe benefits, as well as other direct expenses incurred during the research project. Direct expenses may include the salary of technical associates; the purchase of relevant laboratory supplies; direct expenses necessary for proper conduct of research (e.g. subject-related costs, study-related personnel costs, diagnostic fees/services, data management expenses). Indirect costs may include and travel expenses to scientific meetings, software licensing fees, publication costs etc.

No other government, non-governmental, or industry-sponsored projects may cover the same work scope as the grant application to the ASPIRE Program. However, an ASPIRE HEMOPHILIA Research Program grant may be related to other funding from foundations or government agencies, as long as there is no direct overlap. It is the responsibility of the applicant to justify the novelty of the proposal and provide evidence that the application does not overlap with any current or pending funding. (top)

Can ASPIRE HEMOPHILIA Research funding be used to purchase equipment?
No. ASPIRE HEMOPHILIA Research funds may not be used to purchase equipment, although the purchase of relevant laboratory supplies
is allowed. (top)

Are the ASPIRE HEMOPHILIA Research awards renewable?
No. Each ASPIRE HEMOPHILIA Research award is a one-time, non-renewable research grant. (top)

Are the ASPIRE HEMOPHILIA Research awards open to researchers working outside the United States?
The ASPIRE HEMOPHILIA Research awards are open only to researchers from the United States. (top)

What areas of research meet the criteria for ASPIRE HEMOPHILIA Research funding?
The ASPIRE HEMOPHILIA Research Program seeks to generate exploratory data to better understand disease pathogenesis, risk factors, host response and clinical outcomes in Hemophilia A or Hemophilia B as well as translation of the resulting knowledge to bridge the gap between bench and bedside. (top)

Are there any specific research areas that are excluded from ASPIRE HEMOPHILIA Research funding?
The following topics fall outside of the scope of the ASPIRE HEMOPHILIA Research Program:

What project deliverables are required?
Projects are expected to yield results that will advance the medical knowledge of Hemophilia A or Hemophilia B. It is expected that results will be presented at scientific meetings and published in peer reviewed journals. (top)

Will non-drug research proposals be considered?
Yes. Both drug and non-drug proposals will be considered for funding. (top)

If the study uses a Pfizer drug, what are Pfizer’s procedures for reporting of Serious Adverse Events?
Reporting of Serious Adverse Events is a key responsibility of the Research Award Principal Investigator

For All Studies Using a Pfizer Product and/or Device: Pfizer requires that, within 24 hours of first awareness of the event (or immediately if the event is fatal or life-threatening), the principal investigator will report to Pfizer by facsimile any Serious Adverse Event (SAE) that occurs during the SAE reporting period in a study subject assigned to receive the Pfizer Product. In addition, for studies using a Pfizer device or Pfizer product packaged with a device, reportable events include not only SAEs but also Device Incidents and Device Near-Incidents.

Can an exception be made for certain applicants regarding the eligibility criteria to the ASPIRE HEMOPHILIA Research awards?
The eligibility requirements have been carefully designed to attract appropriate candidates. In keeping with the purpose and intention of the
ASPIRE awards, applicants must meet all the criteria in order to be considered for an award. Submissions outside these parameters will not be considered. (top)

I’m still not sure if my proposed research topic meets the criteria, how can I find out?
Please contact the ASPIRE Coordinator with a brief description of your proposed research area.
Email: questions.aspireresearch-HEMOPHILIA@pfizer.com (top)

Is there a time limit for conducting the funded research?
Study results are expected before each 31 December commencing the year after the award is made. (top)

How do I apply for a ASPIRE HEMOPHILIA Research award?
Applications are to be submitted to Pfizer through an online submission website. Visit www.aspireresearch.org, and click on “2014 Hemophilia Research Awards for US”, click on “Apply”. From there you will be routed to Pfizer’s global investigator-initiated research website. Click on “Submit an IIR Request” and follow the online instructions. Applicants must have “ASPIRE-US 2014” included in the Study Title field in the Study Details section of the online submission portal.

Completed application forms must be accompanied by the following documents:

Where can I get an application form?
The application form can be found at http://www.aspireresearch.org
Alternatively, email questions.aspireresearch-HEMOPHILIA@pfizer.com. (top)

What if I don’t fully understand the ASPIRE application process?
Please refer to the application guide. If you still have questions, please e-mail the coordinator questions.aspireresearch-HEMOPHILIA@pfizer.com (top)

I’m having difficulty submitting my application online, who do I contact for assistance?
Receive assistance by contacting iir@pfizer.com
(top)

What is the deadline for application?
Applications must be received by Monday, 19 May 2014. (top)

When will I hear whether my application has been successful?
Successful applicants will be notified by the Summer. (top)

If my application is successful, when will the funding commence?
Awards will commence on or around November/December, pending receipt of all required documents noted on the application form.
Contracts that are unable to be executed by the end of the calendar year are subject to loss of funding. (top)

Will I receive a copy of the Review Committee’s evaluation of my grant proposal?
A summary review of the independent expert review panel’s comments will be provided to unsuccessful applicants in order to assist them in further refining their grant proposals for possible future submissions. (top)

I have a question that is not covered here?
If you require clarification on an issue not addressed here, please contact the ASPIRE Coordinator,
email: questions.aspireresearch-HEMOPHILIA@pfizer.com (top)

Does Pfizer sponsor other competitive grants programs?
Yes. Therapeutic areas, application dates, deadlines and eligibility vary between programs.
Please visit www.aspireresearch.org for more information. (top)

Can I be notified when future ASPIRE competitive grants program become available?
Visit www.aspireresearch.org and complete the contact information section to receive future program notifications. (top)

I'm a previous ASPIRE Award Winner, am I eligible to apply for another award?
ASPIRE Hemophilia award winners may apply for awards in the future. Awards are based upon scientific merit commensurate with funding that is available. Please inquire questions.aspireresearch-HEMOPHILIA@pfizer.com before applying. (top)