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ASPIRE-Sicklecell Eligibility

Applicants must meet the following requirements. Proposals not meeting the requirements listed below will be rejected.

Academic Eligibility

  • The study must take place entirely in the United States (US) or Canada, and all sites must be located in the United States or Canadian provinces and territories. The Principle Investigator (PI) and sponsoring organization must be located in the US or Canada.
  • The applicant (PI) must have a medical degree (MD or equivalent), an advanced nursing degree (BSN with a MS/PhD), or a degree in Pharmacy, Physiotherapy, or Social Work.

Research Requirements

Applicants/Investigators are expected to:
  • Design studies and generate data to address at least one of the Research Areas of Interest
  • Provide a Publication Plan describing submission of abstracts to (a) congress(es) or submission of (a) publication(s) to peer-reviewed journals. All publications must follow ICH guidelines.
  • Complete the study within 12 to 24 months from the time that the grant is awarded

Criteria for Selection

The ASPIRE Sickle Cell Disease Research Awards will be selected by an independent, external review panel (External Review Committee) comprised of experts in sickle cell disease. In their evaluation, the External Review Committee members will consider:

  • Scientific merit and innovation of the research proposal
  • Potential impact of the research proposal
  • Qualifications of the Applicant
  • Relevance of proposed research to the program's mission
  • Evidence of the Applicant's commitment to an academic research career
  • Evidence of a suitable research environment
Note: A preliminary review of submissions will be completed by Pfizer in order to ensure there are no restrictions (i.e., FDA or Health Canada Restricted) on the Principal Investigator, and that there are no concerns with the proposed work from a patient safety or intellectual property perspective.

Other Funding

No other government, non-governmental, or industry-sponsored projects may cover the same work scope as the grant application to the ASPIRE Program. However, an ASPIRE Program Research Award may be related to other funding from foundations or government agencies, as long as there is no direct overlap. It is the responsibility of the Applicant to justify the novelty of the proposal and provide evidence that the application does not overlap with any current or pending funding.

Once awarded, an ASPIRE Research Award cannot be amended upwards with additional funding support from Pfizer (via the standard Investigator-Initiated Research [IIR] process or separate competitive grant program), nor can additional drug support above and beyond what is sufficient to complete the original study as reviewed and approved by the External Review Committee be provided. If supplemental funding is required, it must be secured from sources outside of Pfizer. Similarly, an ongoing Pfizer supported standard IIR cannot apply for supplemental funding via a Pfizer supported competitive grants program.

ASPIRE Program Research Awards cannot be provided to studies that are already in progress.


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