Pfizer is pleased to announce the 2012 ASPIRE Competitive Research Grant Awards: Narrow Spectrum Antibiotics for the Treatment of MRSA: Clinical Evaluation in Complex Adult Patients

Mission

The mission of the 2012 ASPIRE Awards in Antibacterial Research is to advance the medical knowledge to better understand disease pathogenesis, risk factors, host response and treatment outcomes of linezolid in complex adult patients within approved indications.

Background

Considerable clinical trial data exists for linezolid in a variety of patients with known infections. However, most of this information is from controlled clinical trials and patients with certain disease complexities are underrepresented.

Request for Proposals

Pfizer invites investigators to apply for the 2012 ASPIRE Awards in Antibacterial Research through submission of innovative clinical research proposals that evaluate linezolid’s role in the treatment of infections in complex adult patients within approved indications.

2012 Research Topic

Narrow Spectrum Antibiotics for the Treatment of MRSA: Clinical Evaluation in Complex Adult Patients

Research Requirements

An applicant should have a strong academic career interest within the areas of focus and should consider the following components when developing their research proposals:

A. Clinical evaluations of linezolid within the following disease states: B. Clinical evaluations of linezolid within patient populations with the following complexities: C. Clinical evaluations of linezolid within the following sub-populations or areas of interest: D. The following topics fall outside of the scope of the ASPIRE Antibacterial Research Program:

Research Expectations

Within the specified patient populations with infection types of interest, investigators are expected to:

Well-designed retrospective analyses are preferred however, small pilot studies that attempt to test hypotheses will be considered as long as the study can be completed within 1 year.

Investigators may consider evaluating additional clinical measures (e.g. length of stay, readmission, ventilator days, etc.). However, proposals seeking to financially quantify outcomes are outside the scope of the program. See FAQ’s for guidance.

Available Awards

Pfizer is funding awards from $50,000 to a maximum of $100,000* (including direct costs, institutional overhead costs, and indirect costs) each for one year to conduct research generating data that will lead to a better understanding of the safety and efficacy of linezolid in complex patients within approved indications.

*Please note that study budgets will be evaluated separately to ensure the requested funding is commensurate with the work proposed.

Deadline for Application

Applications must be received by 11:59pm EST on May 1, 2012.