What specific areas of research meet the criteria for CML ASPIRE research funding?

What areas of research meet the criteria for CML ASPIRE research funding?
The following areas are in scope for the 2015 program:

  • Optimization of monitoring in bosutinib-treated CML patients, incorporating next generation technologies (such as deep-sequencing and gene profiling)
  • Early switch to bosutinib in CML TKIs treatment and patients outcome in 2L setting after switching from 1L treatment
  • Identification of appropriate biomarkers associated with safety or efficacy, can be either predictive or prognostic or otherwise useful to guide therapy among CML TKIs including bosutinib
  • Mechanism of bosutinib-associated adverse events such as diarrhea or Cardiovascular events
  • Individualized dose optimization for bosutinib treatment (2L and above)
  • Quality of life and Patients-Reported Outcomes among CML patients treated with TKIs including bosutinib. (top)

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criteria