ASPIRE-Hemophilia Landing Page

Pfizer announces the 2017 U.S. ASPIRE Hemophilia Research Awards Program

Background

The 2017 U.S. Advancing Science through Pfizer: Investigator Research Exchange (ASPIRE) Hemophilia Research Awards Program is a competitive grants program that reflects the commitment of Pfizer Hemophilia to support ongoing basic science and clinical investigation in hemophilia A and B.

Ongoing basic science research and clinical research are critical to deepen understanding of disease mechanisms and to ensure advancement of management strategies for hemophilia A and hemophilia B and their related comorbidities. In an era of increased competition for research funding, the 2017 U.S. ASPIRE Hemophilia Research Awards Program is designed to support laboratory and clinical research in pathogenesis, complications, management, and clinical outcomes of hemophilia A and B.

Mission

  • To advance basic science, translational and clinical research through a competitive grants program that increases medical knowledge in the pathogenesis, complications, management, and clinical outcomes of hemophilia A and B.
  • To support academic research as well as the career development of promising young and established scientists.

Areas of Research Focus

Pfizer will consider proposals for research projects which address one of the following areas in hemophilia A and/or hemophilia B.  Applications comprising laboratory investigation or clinical research will be considered.
  • Real-world analyses of factor replacement product usage
  • Clinical outcomes in non-severe hemophilia
  • Musculoskeletal Health, including musculoskeletal ultrasound
  • Impact of physical activity/exercise including coordination of preventative factor regimens using standard half-life products
  • Bleeding phenotype, access to care, and social issues concerning (1) carriers (2) aging persons with hemophilia
  • Alternative hemostatic pathways
  • Gene therapy for hemophilia
  • Significance and location of extravascular coagulation FIX stores

Application and Selection Process

The 2017 U.S. ASPIRE Program is open to U.S. investigators. Review of grant proposals will be performed by an independent, external panel of experts. Project duration should be 1 or 2 years and the annual approximate award will be up to $100,000/year, inclusive of overhead costs (capped at 28%). Special consideration will be given to early-career (e.g., fellows, junior faculty) applicants.

Proposals must be received by March 31, 2017.